000			01729nam a22002177a 4500
005			20240316114125.0
008			240316b ||||| |||| 00| 0 eng d
020			_a9783030111410
040			_cAL
041			_aeng
082			_223 _a574.19245 _bBUXF
100			_aEngelbert Buxbaum _9154870
245			_aFundamentals of protein structure and function
250			_a2nd ed.
260			_aNew York _bSpringer _c2019
300			_axvi,521p. _bHB _c24x15cm.
365			_2General _a7743 _b₹2396.00 _c₹ _d₹2995.00 _e20% _f15-02-2024
520			_aThis book serves as an introduction to protein structure and function. Starting with their makeup from simple building blocks, called amino acids, the 3-dimensional structure of proteins is explained. This leads to a discussion how misfolding of proteins causes diseases like cancer, various encephalopathies, or diabetes. Enzymology and modern concepts of enzyme kinetics are then introduced, taking into account the physiological, pharmacological and medical significance of this often neglected topic. This is followed by thorough coverage of hæmoglobin and myoglobin, immunoproteins, motor proteins and movement, cell-cell interactions, molecular chaperones and chaperonins, transport of proteins to various cell compartments and solute transport across biological membranes. Proteins in the laboratory are also covered, including a detailed description of the purification and determination of proteins, as well as their characterisation for size and shape, structure and molecular interactions. The book emphasises the link between protein structure, physiological function and medical significance.
650			_2Biochemistry _aLife Sciences _9154871
942			_2ddc _cBK
999			_c230454 _d230454