000			02033nam a22002177a 4500
005			20220330104547.0
008			220328b ||||| |||| 00| 0 eng d
020			_a9789351073352
040			_cAL
041			_aeng
082			_223 _a541.39 _bANDP
100			_aNeal G Anderson _926331
245			_aPractical Process Research and Development _bA guide for organic chemists
250			_a2nd ed.
260			_aNew Delhi _bElsevier _c2012
300			_axi,475p. _bHB _c23.5x16cm.
365			_2General _a6556 _b₹2396.00 _c₹ _d₹2995.00 _e20% _f19/03/2022
520			_aDesigned to provide a comprehensive, step-by-step approach to organic process research and development in the pharmaceutical, fine chemical, and agricultural chemical industries, this book describes the steps taken, following synthesis and evaluation, to bring key compounds to market in a cost-effective manner. It describes hands-on, step-by-step, approaches to solving process development problems, including route, reagent, and solvent selection; optimising catalytic reactions; chiral syntheses; and "green chemistry.Second Edition highlights: • Reflects the current thinking in chemical process R&D for small molecules • Retains similar structure and orientation to the first edition. • Contains approx. 85% new material • Primarily new examples (work-up and prospective considerations for pilot plant and manufacturing scale-up) • Some new/expanded topics (e.g. green chemistry, genotoxins, enzymatic processes) • Replaces the first edition, although the first edition contains useful older examples that readers may refer to Provides insights into generating rugged, practical, cost-effective processes for the chemical preparation of "small molecules".Breaks down process optimization into route, reagent and solvent selection, development of reaction conditions, workup, crystallizations and more. Presents guidelines for implementing and troubleshooting processes
650			_2Physical chemistry _aChemistry _926574
942			_2ddc _cBK
999			_c222058 _d222058