Freifelders essentials of molecular biology (Record no. 121330)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 07850nam a2200241Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250408154019.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 210210b2015 xxu||||| |||| 00| 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9789384323059 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | AL |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 574.88 MALF |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | MALACINSKI (George M) |
| 9 (RLIN) | 59115 |
| 245 ## - TITLE STATEMENT | |
| Title | Freifelders essentials of molecular biology |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 4 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | New Delhi |
| Name of publisher, distributor, etc. | Jones & Bartlett |
| Date of publication, distribution, etc. | 2015 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | xix,491 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Description:<br/><br/>Essentials of Molecular Biology, Fourth Edition focuses on the fundamental aspects of molecular structure and function by reviewing key features, and along the way, capsulizing them as a series of concise concepts. Thus, students are encouraged to place the essential knowledge of molecular biology into broad contexts and thereby develop both academic and personal meaning for this discipline.<br/><br/>Essentials of Molecular Biologyis organized into a series of modules that provides instructors with an opportunity to scale the treatment of various topics up or down, depending on the level of the students and the overall curriculum format.<br/><br/><br/>Module Themes:<br/><br/>The Structure of Proteins, Nucleic Acids, and Macromolecular Complexes<br/>Function of Macromolecules<br/>Coordination of Macromolecular Function in Cells<br/>Experimental Manipulation of Macromolecules |
| 521 ## - TARGET AUDIENCE NOTE | |
| Target audience note | Contents:<br/><br/>About the Author • Preface • Prologue<br/>Chapter 1: Welcome to Molecular Biology! • Goals of Molecular Biology • The Early Years • Model Biological Systems • Methodology of Molecular Biology • Rapid Progress in Molecular Biology • Putting the Details of Molecular Biology in Perspective • Concepts of Molecular Biology • Progression Diagram • Rewards from Studying Molecular Biology<br/>Part I: The Structure of Proteins, Nucleic Acids, and Macromolecular Comlexes<br/>Chapter 2: Macromolecules • Chemical Structures of the Major Classes of Macromolecules • Noncovalent Interactions That Determine the Three-Dimensional Structures of Proteins and Nucleic Acids • Macromolecule Isolation and Characterization<br/>Chapter 3: Nucleic Acids • Physical and Chemical Structure of DNA • Alternate DNA Structures • Circular and Superhelical DNA • Renaturation • Hybridization • The Structure of RNA • Hydrolysis of Nucleic Acids • Sequencing Nucleic Acids • Synthesis of DNA • A Future Practical Application?<br/>Chapter 4: The Physical Structure of Protein Molecules? Basic Features of Protein Molecules • The Folding of a Polypeptide Chain • The a Helix and ?? Secondary Structures • Protein Structure • Proteins with Subunits • Enzymes • A Future Application<br/>Chapter 5: Macromolecular Interactions and the Structure of Complex Aggregates? A Complex DNA Structure: The E. coli Chromosome • Chromosomes and Chromatin • Interaction of DNA and Proteins That Recognize a Specific B • Sequence • Biological Membranes • Cytoskeletal Elements • A Future Practical Application?<br/><br/>Part II: Function of Macromolecules<br/>Chapter 6: The Genetic Material? Early Observations on the Mechanism of Heredity • Identification of DNA As the Genetic Material • Identification of RNA As the Genetic Material of Certain Viruses • Properties of the Genetic Material • RNA As the Genetic Material<br/>Chapter 7: DNA Replication • Semiconservative Replication of Double-Stranded DNA • Untwisting of Highly Coiled DNA Is Required for DNA Replication • Initiation of DNA Replication • Unwinding of DNA for Replication • Elongation of Newly Synthesized Strands • DNA Polymerase III Consists of Multiple Subunits • Antiparallel DNA Strands and Discontinuous Replication • The Complete DNA Replication System • Replication of Eukaryotic Chromosomes • A Future Practical Application?<br/>Chapter 8: Transcription • Enzymatic Synthesis of RNA • Transcription Signals • Classes of RNA Molecules • Transcription in Eukaryotes • Means of Studying Intracellular RNA • A Future Practical Application?<br/>Chapter 9: Translation • Outline of Translation • The Genetic Code • The Wobble Phenomenon • Polycistronic mRNA • Overlapping Genes • Polypeptide Synthesis • Stages of Polypeptide Synthesis in Prokaryotes • Complex Translation Units • Antibiotics • A Future Practical Application?<br/>Chapter 10: Mutations, Mutagenesis, and DNA Repair? Types of Mutations • Biochemical Basis of Mutants • Mutagenesis • Induced Mutations • Reversion • Reversion As a Means of Detecting Mutagens and Carcinogens • DNA Repair Mechanisms • Spontaneous Mutations and Their Repair • Repair by Direct Reversal • Excision Repair • Recombinational Repair • The SOS Response • Future Practical Applications?<br/><br/>Part III: Coordination of Macromolecular Function in Cells<br/>Chapter 11: Regulation of Gene Activity in Prokaryotes? Principles of Regulation • Transcriptional Regulation • Posttranscriptional Control • Feedback Inhibition and Allosteric Control • A Future Practical Application?<br/>Chapter 12: Regulation of Gene Activity in Eukaryotes? Important Differences in the Genetic Organization of Prokaryotes and Eukaryotes • The Regulation of Transcription Initiation • The Regulation of RNA Processing • Regulation of Nucleocytoplasmic mRNA Transport • Regulation of mRNA Stability • Regulation of Translation • Regulation of Protein Activity • Gene Rearrangement: Joining of Coding Sequences in the Immune System • A Future Practical Application?<br/>Chapter 13: Genomics and Proteomics Drive Information-Age Biology? Genomics- The Use of DNA As a Starting Point for Discovery • Bioinformatics-Using DNA Sequence Information to Build Knowledge • Proteomics Focuses on the Totality of Proteins: Their Numbers, Structures, Interactions, Locations, and Functions • The Emergence of a New ?Logic of Molecular Biology?? • A Future Practical Application?<br/><br/>Part IV: Experimental Manipulation of Macromolecules<br/>Chapter 14: Transposons, Plasmids, and Bacteriophage? Transposable Elements-Their Discovery Surprised Molecular Biologists • Transposable Elements in Eukaryotes • Plasmids • Plasmid-Borne Genes • Plasmid Transfer • Plasmid DNA Replication • Bacteriophage • Stages in the Lytic Life Cycle of a Typical Phage • Specific Phage • Transducing Phage • Transposons, Plasmids, and Bacteriophage in Genetic Engineering • A Future Practical Application?<br/>Chapter 15: Recombinant DNA and Genetic Engineering: Molecular Tailoring of Genes? Plasmids Act As Nature's Interlopers • Restriction Enzymes Function As Nature's Pinking Shears • Genetic Interlopers: Vectors Function As Vehicles for Transferring Genes • Detection of Recombinant DNA Molecules • Site-Specific Mutagenesis Using Bacteriophage M- 13 Vector • Applications of Genetic Engineering<br/>Chapter 16: Molecular Biology Is Expanding Its Reach? Uses of Recombinant DNA Technology in Research • Uses of Recombinant DNA Technology in Medicine • Uses of Recombinant DNA Technology in Agriculture • Other Commercial and Industrial Applications • Molecular Biology: On the Front Line of the Battle Against AIDS • Social and Ethical Issues<br/>POSTSCRIPT: Postscript to Your Review of Molecular Biology? Molecular Biology Is Enjoying a Golden Era! • Speculation-Let's Anticipate a Few Discoveries in Molecular Biology! • Enhance Your Ability to Learn Molecular Biology! • Consider Becoming a Molecular Biologist!<br/>APPENDIX: Chemical Principles Important for Understanding Molecular Biology • Structure of the Atom • Chemical Bonds • The Ionization of Water-The pH Scale • Organic Chemistry • Concluding Note<br/>List of Essential Concepts<br/>Glossary<br/>Answers to Questions and Problems<br/>Index<br/> |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Molecular Biology |
| 9 (RLIN) | 59116 |
| 906 ## - LOCAL DATA ELEMENT F, LDF (RLIN) | |
| a | 071587 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Book |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection code | Home library | Current library | Date acquired | Source of acquisition | Cost, normal purchase price | Total Checkouts | Full call number | Barcode | Date last seen | Date last checked out | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | Bio Chemistry | St Aloysius Library | St Aloysius Library | 02/17/2021 | Super Book Services, Near Bangalore University, Bangalore-560056 | 595.00 | 1 | 574.88 MALF | 071587 | 04/03/2024 | 03/25/2024 | 02/17/2021 | Book |
